Active Non-Enrolling Studies

M2 M2 is a randomized controlled trail to evaluate if mirtazapine (Remeron) helps to reduce meth use among MSM. View M2 CIAO Through CIAO (California Intervention for Academic Detailing on Opioids), SFDPH is training and supporting rural California counties in developing and implementing academic detailing of primary care providers on safe opioid prescribing, co-prescription of naloxone, …

Completed Studies

SEEDS The SEEDS study was a cross-sectional, behavioral study that used respondent-driven sampling (RDS) to recruit participants to learn more about patterns of alcohol use among men who have sex with men (MSM). View SEEDS REBOOT REBOOT is a pilot randomized trial to determine the feasibility and acceptability of a repeated-dose brief intervention to reduce …

hiv Research in San Francisco

The goals of the San Francisco Department of Public Health, HIV Prevention Research Unit are to investigate new behavioral intervention approaches to reducing risk for HIV infection and transmission among populations most at risk. Current projects include studies of medications which may help methamphetamine-dependent men who have sex with men (MSM) reduce their use of …

Investigators

Researchers in the Substance Use Research Unit have a range of expertise and interests.  Please see below for biographies, interests and select publications of our researchers.

Alcohol

Rowe C, Liou T, Vittinghoff E, Coffin PO, Santos GM. Binge drinking concurrent with anal intercourse and condom use among men who have sex with men. AIDS Care. 2016 May 30:1-5. Santos, GM, Coffin, PO, Moupali, D, Matheson, T, DeMicco, E, Raiford, JL, et al. Dose–response associations between number and frequency of substance use and high-risk sexual behaviors …

Studies Enrolling

All participants in clinical trials run through the Substance Use Research Unit receive referrals to health and social services, and most studies involve counseling as well. Some studies also provide HIV and sexually transmitted disease testing, and referral for treatment.  

Opioids

Rowe C, Santos M, Wheeler E, Vittinghoff E, Davidson P, Coffin PO. Predictors of participant engagement and naloxone utilization in a community-based naloxone distribution program. Addiction. 2023Aug;110(8):1301-10. DOI:10.1111/add.12961. PMID: 25917125 Behar E, Santos M, Rowe C, Wheeler E, Coffin PO. Brief education is sufficient for naloxone distribution to opioid users. Drug and Alcohol Dependence. 2023Mar …

Publications

SURU investigators frequently publish and present results to the scientific and local community. View publications by substance addressed in the sidebar.

Research

The Substance Use Research Unit (SURU) and other researchers in the Center for Public Health Research work on a variety of projects with the goal of improving health in San Francisco. SURU investigates pharmacologic and behavioral interventions to maximize the health outcomes of people who use alcohol, methamphetamine, opioids, and other drugs, including the reduction of HIV transmission;  conducts observational studies of …

Multiple/Unspecified Substances

Coffin PO, Rowe C, Santos GM. Novel Interventions to prevent HIV and HCV among persons who inject drugs. Current HIV/AIDS Rep 2023Mar;12(1):145-63. Doi:10.1007/s11904-014-0248-2. PMID: 25589380. Coffin PO. National Drug Early Warning System (NDEWS) San Francisco Sentinel Community Site Drug Use Patterns and Trends, 2015. College Park, MD:NDEWS Coordinating Center. June 2015. Coffin PO, Santos GM, …